Engineering Tumor-Targeted Therapies

Forbes Research Group

at the University of Massachusetts Amherst

Selected Publications

Forbes NS, Munn LL, Fukumura D, Jain RK, 2003.  Sparse initial entrapment of systemically injected Salmonella typhimurium leads to heterogeneous accumulation within tumors.  Cancer Res. 63:5188-5193.

Helmlinger G, Sckell A, Dellian M, Forbes NS, Jain RK. 2002. Acid production in variant, glycolysis-deficient and parental tumors in vivo: support for hypothesized tumor metabolism. Clin. Cancer Res. 8:1284-1291.

Jain RK, Forbes NS. 2001. Can engineered bacteria help control cancer? PNAS 98:14748-14750.

Forbes NS, Clark DS, Blanch HW. 2001. Using isotopomer path tracing to quantify metabolic fluxes in pathway models containing reversible reactions. Biotech. Bioeng. 74:196-211.

Forbes NS, Clark DS, Blanch HW. 2000. Analysis of metabolic fluxes in mammalian cells. Chap 4.4 in: Schügerl K, Bellgardt KH, editors. Bioreaction Engineering: Modeling and Control. Berlin: Springer Verlag.

 

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