ChE
697A Molecular and Systems
Biotechnology
Department of Chemical Engineering
Spring, 2005
Schedule |
Reading List
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| Time: |
TTh 2:30-3:45pm
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| Lectures: |
Lederle 201
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| Office
hours: |
Appointment by email
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| TA: |
None
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| Textbooks
and
handouts: |
No textbook is required.
Class notes and reading assignments will
be posted on the course web site before each class.
|
| Grading: |
10%
paper presentation, 30% project presentations and 60% project report.
|
| Email: |
All students are required to
send Lianhong Sun an email message by 1/31/05. Include your preferred
email address. We will use email to
announce schedule changes, update of the web site, etc.
|
| Attendance: |
All students are expected
to attend each class on time.
|
| Course
objectives: |
- Introduction to the
principles of molecular and systems biotechnology.
- Highlight current
progress and future
directions in molecular and
systems biotechnology.
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| Course
outcomes: |
- Become
familiar with the concepts of applied biocatalysis and its current
status in the
chemical and pharmaceutical industries.
- Gain
a deep insight into protein engineering principles. Understand the
strengths
and constraints of three protein design methods: De novo
design, rational design and directed evolution. Know
how to change properties of enzymes using
related technologies, such as display technologies, genetic screen and
selection, incorporation of unnatural amino acids.
- Understand
how to use chemical biology methods to illuminate protein-protein
interaction,
synthesize small molecules with desired properties, and label
biological
systems.
- Be
able to analyze genetic circuits and design simple artificial genetic
systems.
- Develop
an understanding of the theoretical underpinnings and the application
of
metabolic flux and control analysis.
- Become
familiar with nonlinear modeling and analysis techniques for genetic
regulatory, signal transduction and metabolic networks.
- Develop
a sufficient command of the literature on molecular and systems
biotechnology
to pursue further studies.
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| News: |
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May 11, 2005: The lecture note and reading assignments for the lecture 26 were posted. |
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May 9, 2005: The lecture note and reading assignments for the lecture 25 were posted. |
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May 4, 2005: The lecture note and reading assignments for the lecture 24 were posted. |
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May 2, 2005: The lecture note and reading assignments for the lecture 23 were posted. |
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April 25, 2005: The lecture note and reading assignments for the lecture 22 were posted. |
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April 22, 2005: The lecture note and reading assignments for the lecture 21 were posted. |
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April 18, 2005: The lecture note and reading assignments for the lecture 20 were posted. |
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April 13, 2005: The lecture note and reading assignments for the lecture 19 were posted. |
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April 11, 2005: The lecture note and reading assignments for the lecture 18 were posted. |
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April 4, 2005: The lecture note and reading assignments for the lecture 17 were posted. |
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March 30, 2005: The lecture note and reading assignments for the lecture 16 were posted. |
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March 28, 2005: The lecutre note and reading assignments for the lecture 15 were posted. |
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March 23, 2005: The lecture note and reading assignments for the lecture 14 were posted. |
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March 20, 2005: The lecture note and reading assignments for the lecture 13 were posted. |
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March 18, 2005: The lecture note and reading assignments for the lecture 12 were posted. |
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March 07, 2005: The lecture notes and reading assignments for the lecture 10 & 11 were posted. |
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February 23, 2005: Project proposal writing guidline and template were posted. |
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February 21, 2005: The
lecture notes and reading assignments for the Lectures 8&9 were
posted.
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February 16, 2005: The
lecture note and reading assignments for the Lecture 7 were posted. |
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February 14, 2005: There
was a slight change of schedule. Please read the new schedule.
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February 14, 2005: The
lecture note and reading assignments for the Lecture 6 were posted.
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February 9, 2005: The
lecture note and reading assignments for the Lecture 5 were posted.
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February 7, 2005: The
lecture note and reading assignments for the Lecture 4 were posted.
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February 3, 2005: Two
reference books (linked to Amazon.com) were added.
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February 2, 2005: The
lecture note and reading assingments for the Lecture 3 were posted.
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January 27, 2005: The
lecture note and reading assignments for the Lecture 2 were posted.
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January 26, 2005: Reading list, the first lecture note,
and readling assignments were posted.
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January
17,2005: This web site was created.
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Reading
Assignments:
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Lecture_26 (MAH): 1, 2, 3, 4 |
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Lecture_25 (MAH): 1, 2, 3, 4, 5 |
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Lecture_24 (MAH): 1, 2, 3, 4, 5 |
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Lecture_23 (MAH): 1, 2, 3 |
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Lecture_22 (MAH): 1, 2, 3 |
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Lecture_21 (MAH): 1, 2, 3, 4, 5 |
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Lecture_20 (LS): 1, 2, 3, 4 |
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Lecture_19 (LS): 1, 2, 3, 4 |
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Lecture_18 (MAH): 1, 2 |
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Lecture_17 (MAH): 1, 2, 3, 4, 5 |
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Lecture_16 (MAH): 1, 2, 3, 4 |
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Lecture_15 (MAH): 1 |
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Lecture_14 (LS): 1, 2, 3 |
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Lecture_13 (LS): 1, 2, 3, 4, 5, 6 |
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Lecture_12 (LS): 1, 2, 3 |
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Lecture_11 (LS): 1, 2, 3, 4, 5, 6,7,8 |
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Lecture_10 (LS): 1, 2 |
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Lecture 9 (LS): 1
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Lecture 8 (LS): 1, 2,
3,
4,
5,
6
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Lecture 7 (LS): 1,
2,
3,
4,
5,
6,
7
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Lecture 6 (LS): 1,
2,
3,
4
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Lecture 5 (LS): 1, 2,
3, 4
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Lecture 4 (LS): 1,
2,
3,
4
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Lecture 3 (LS): 1,
2,
3
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Lecture 2 (MAH): 1, 2, 3
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Lecture 1(LS): 1, 2, 3
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Copyright
|
The copyright of the pictures
and articles used in the course belongs to the original authors and
publishers. Use of these materials is limited to the purpose of this
course only. Distribution of class materials without written permission
from the original owners is strictly prohibited.
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This
site is best viewed by Netscape 7.2. Please email Professor Lianhong Sun for any problems and comments .
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